Danazol: An Effective Option in Acquired Amegakaryocytic Thrombocytopaenic Purpura
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منابع مشابه
Danazol: An Effective Option in Acquired Amegakaryocytic Thrombocytopaenic Purpura
Acquired amegakaryocytic thrombocytopaenic purpura (AATP) is a rare haematological condition characterised by isolated thrombocytopaenia with normal other cell lines. It is often initially misdiagnosed as immune thrombocytopaenic purpura but has characteristic bone marrow findings of reduced megakaryocyte numbers. The optimal treatment of AATP is not clearly defined but revolves around immunosu...
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Acquired Amegakaryocytic Thrombocytopenic Purpura (AATP) is a rare cause of thrombocytopenia presenting over a wide age group with symptoms of bleeding and bone marrow showing isolated absence of megakaryocytes in an otherwise normal marrow. Here, we report a case of AATP in a three year old female child who was then treated with anti thymocyte globulin successfully. We report this case because...
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Acquired amegakaryocytic thrombocytopenic purpura (AATP) is a disorder of hematopoiesis characterized by severe thrombocytopenia due to a selective reduction or total absence of megakaryocytes in an otherwise normal-appearing bone marrow. Although the development of autoantibodies directed against cells in the megakaryocyte progenitor cell pool has been implicated in the pathogenesis of this di...
متن کاملAcquired amegakaryocytic thrombocytopenic purpura: a syndrome of diverse etiologies.
The possible pathogenetic mechanisms responsible for the production of acquired amegakaryocytic thrombocytopenic purpura (AATP) were investigated in a group of patients with this disorder. Absence of megakaryocytes and small platelet glycoprotein-bearing mononuclear cells, as determined by immunochemical staining of patient marrows with an antisera to platelet glycoproteins, suggested that the ...
متن کاملPregnancy in women with idiopathic thrombocytopaenic purpura.
INTRODUCTION Idiopathic thrombocytopaenic purpura (ITP) is a common haematological disorder in young women. The management of ITP in pregnancy is controversial, particularly with regards to the mode of delivery. To date, there is no systematic study of the outcome of these pregnancies in Singapore. AIM To study the outcomes of pregnancies in Asian women with a proven diagnosis of ITP. MATER...
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ژورنال
عنوان ژورنال: Case Reports in Hematology
سال: 2015
ISSN: 2090-6560,2090-6579
DOI: 10.1155/2015/171253